These entries represent interventions that did not show a statistically significant extension of median or maximum lifespan in mouse studies.

This table summarizes key findings from preclinical longevity studies conducted exclusively in mice. All data come from controlled laboratory experiments, and some entries include illustrative “human” values based on rough model-derived conversions to “human years” or equivalent doses; these are approximate and not clinical predictions or recommendations. To date, no human clinical trial has demonstrated lifespan extension, and none of the interventions listed here are approved for that purpose. These interventions remain experimental, may carry risks, and have important limitations when extrapolated from mice to humans. This information is for educational and entertainment purposes only and is not medical advice. Always consult a qualified healthcare professional before considering any treatment, supplement, or off-label drug use.